Tsp 1 antibody
WebThe cells were labeled with Thrombospondin 1 (D4.6) Mouse Monoclonal Antibody (Product # MA5-13385) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then ... * P . 0*010 (Student's t test). e Western blotting of thrombospondin (TSP) 1 protein at 6 h after hepatectomy. Expression of TSP-1 was similar in normal saline ... WebHere we characterize a novel TSP-1 interaction with T. cruzi that enhances cellular infection. We show that labeled TSP-1 interacts specifically with the surface of T. cruzi trypomastigotes. We used TSP-1 to pull down interacting parasite surface proteins that were identified by mass spectrometry.
Tsp 1 antibody
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WebThe Human TSP-1 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the … Webfragments in digest of Ca2+-replete TSP which are absent from digest in EDTA.1Its binding to TSP is enhanced by EDTA i.e. at low [Ca2+]. 1 It shows no cross-reaction with fibronectin, fibrinogen, TSP-2 and von Willebrand factor. Mol. Wt. of Antigen: ~450kDa (non-reduced) 170 to 180kDa (reduced) Epitope: Calcium-binding domain of TSP (C-
WebApr 9, 2024 · The perception of human T-cell leukemia virus type 1 (HTlV-1) infection as a “silent disease” has recently given way to concern that its presence may be having a variety of effects. HTLV-1 is known to cause adult T-cell leukemia (ATL), an aggressive cancer of peripheral CD4 T cells; however, it is also responsible for HTLV-1-associated …
WebThrombospondin-1 (TSP-1) is a secreted homotrimeric protein that regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and anti-thrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 ... WebApr 11, 2024 · Thrombospondin4 (TSP4) is a 140 kDa calciumbinding protein that interacts with other extracellular matrix molecules and modulates the activity of various cell types. TSP1 and 2 constitute subgroup A and form disulfidelinked homotrimers, whereas TSP3, 4, and 5/COMP constitute subgroup B and form pentamers (1, 2).
WebThrombospondin-1 (TSP-1) is a 150‑180 kDa charter member of the thrombospondin family of extracellular matrix proteins. Human TSP‑1 is synthesized as an 1170 amino acid (aa) precursor that contains an 18 aa signal sequence and 1152 aa mature molecule. The mature molecule has been described as containing three distinct regions that create ...
WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-Thrombospondin 1 antibody [EPR22927-54] (ab267388) Research with confidence – consistent and … can i develop ibs later in lifeWebA purified peptide of the CD47-binding TSP-1 C-terminal domain (E3T3C1) or functional blocking antibodies to TSP-1 (α-TSP-1 C-terminus) or CD47 (α-CD47) were incubated with MVs for 48 hours. Effects of antibody treatment of knockout-derived MVs were not determined (n.d.). can i develop food allergies later in lifeWebNov 11, 2024 · The recombinant TSP-1 protein promoted proliferation, survival, and migration of CTCL cell lines, and anti-CD47 or anti-TSP-1 neutralizing antibody inhibited … fit someone wellWebJan 28, 2024 · Macrophage-mediated phagocytosis of liver cancer cells can be enhanced by treatment with an anti-CD47 antibody, a SIRPα blocking antibody, or by blocking the CD47-TSP-1 interaction (64, 65). Attenuation of CD47-SIRPα signaling in cholangiocarcinoma promotes the phagocytotic potential of a variety of macrophage subpopulations and … fitsok merino crewWebFeb 21, 2024 · This is a Validated Antibody Database (VAD) review about human thrombospondin 1, based on 44 published articles (read how Labome selects the articles), using thrombospondin 1 antibody in all methods.It is aimed to help Labome visitors find the most suited thrombospondin 1 antibody. Please note the number of articles fluctuates … fitsom sacramentoWebLyophilized or Liquid. Concentration. - 100 μg (in 100 μl): 1 mg/ml. Storage. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at … can i develop asthmaWebBackground: Thrombospondin-1 (TSP-1) has been implicated in many different processes based in part on inhibitory activities of anti-TSP-1 monoclonal antibodies (mAbs). … fit something