WebThe most widely used protocol is the treatment of protected lactols (i.e., C) with appropriate chlorosilane (silyl chloride) and imidazole. 343 For those less reactive anomeric hydroxyl … Webtert-Butyldimethylsilyl chloride reacts selectively with hydroxyl groups in nucleosides and preferen- tially with the 5'-hydroxyl of deoxynucleosides. The tert-butyldimethylsilyl group can be removed under conditions which do not affect other commonly used acid or base labile protecting groups, yet it is stable to phosphorylation conditions.

Tert-Butyldimethylsilyl Group - an overview ScienceDirect Topics

Webtert-Butyldimethylsilyl chloride (TBDMSCl) is an organosilicon compound that can be used as a versatile protecting reagent for alcohols, amines, amides, and various carboxylic … WebTert-butyldimethylsilyl chloride is a silyl chloride consisting of a central silicon atom covalently bonded to one chloro, one tert-butyl, and two methyl groups. Tert-butyldimethylsilyl chloride is used for derivatizing compounds for gas chromatography/mass spectrometry applications. brigstons new orleans

Tert-Butyldimethylsilyl chloride C6H15ClSi - PubChem

WebGiven the need for a method that would afford the alternate racemic diols, the bulky silyl protecting group tert -butyldiphenylsilyl (TBDPS) was introduced with the expectation that … WebSAFETY DATA SHEET Creation Date 30-Apr-2010 Revision Date 14-Feb-2024 Revision Number 2 1. Identification Product Name tert-Butyldiphenylchlorosilane Cat No. : A12721 … WebThis paper describes an effective additive, [tert-butyl(diphenyl)silyl] trifluoromethanesulfonate. The results reveal that the additive can be preferentially … brigstow bristol