Webb20 aug. 2016 · Conclusions: PhIP mediates gene expression changes within the adipocyte, and the pathways most affected are related to cancer and other chronic diseases. Further studies are needed on the relationship between dietary carcinogens such as PhIP with cancer, obesity and diabetes. WebbGenes with positive D scores are more likely to be associated with autism risk, with higher-confidence genes having higher D scores. This statistic was first presented by Zhang & Shen (Hum Mutat 38, 204- 215 (2024), and D scores for more than 20,000 RefSeq genes can be found in column M in supplementary table 2 from that paper.
Gene: PHIP
WebbNine patients with microdeletions spanning the 6q14.1 region including the PHIP gene have been reported with a similar phenotype including developmental delay, intellectual disability,hypotonia,andobesity(Beckeretal.2012;Wentzeletal.2010).However,patients with microdeletions encompassing the PHIP gene have a number of additional clinical find- WebbPhip Gene Detail Summary Symbol. Phip Name. pleckstrin homology domain interacting protein. ... Gene Model ID Feature Type Coordinates Select Strains; C57BL/6J: … high-mobility group box 1 protein
Entry - #617991 - CHUNG-JANSEN SYNDROME; CHUJANS - OMIM
WebbChung-Jansen syndrome is a rare disorder- also called PHIP-related disorder. The syndrome is caused by a heterozygous mutation along the PHIPgene. Individuals with … Webb2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is the most abundant heterocyclic amine contained in cooked meat and fish. Although PhIP has been demonstrated to induce various types of tumors in rats, lymphomas predominated in mice using the CDF1 strain. To investigate the carcinogenic activity of PhIP on other organs in mice with a different … Webb13 nov. 2024 · Variants in the pleckstrin homology domain-interacting protein (PHIP) gene are implicated in the clinical phenotype of Chung–Jansen syndrome, which includes … high-motionblur什么意思