Orbactive wiki
WebORBACTIV® (oritavancin) for injection is indicated for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused or suspected to be caused by susceptible isolates of the following gram-positive microorganisms: Staphylococcus aureu s (including methicillin-susceptible [MSSA] and -resistant [MRSA] … WebSep 3, 2024 · The empirical formula of oritavancin diphosphate is C86H97N10O26Cl3•2H3PO4 and the molecular weight is 1989.09. ORBACTIV is supplied as a sterile white to off-white lyophilized powder for intravenous infusion that contains oritavancin diphosphate, mannitol (an inactive ingredient) and phosphoric acid (to adjust …
Orbactive wiki
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Weboritavancin (Rx) Brand and Other Names: Kimyrsa, Orbactiv Classes: Glycopeptides Dosing & Uses AdultPediatric Dosage Forms & Strengths injection, lyophilized powder for reconstitution... WebAug 7, 2014 · ORBACTIV approval is based on the results of the SOLO I and SOLO II clinical studies which were randomized, double-blind, multicenter trials that evaluated a single 1200 mg IV dose of ORBACTIV for ...
WebFeb 22, 2024 · Orbactiv (oritavancin) for injection is an antibiotic used to treat adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible … WebCOMMON BRAND NAME(S): Kimyrsa, Orbactiv. USES: This medication is an antibiotic used to treat serious bacterial infections of the skin. It works by stopping the growth of …
Oritavancin, sold under the brand name Orbactiv among others, is a semisynthetic glycopeptide antibiotic medication for the treatment of serious Gram-positive bacterial infections. Its chemical structure as a lipoglycopeptide is similar to vancomycin. The U.S. Food and Drug Administration (FDA) and … See more Oritavancin shares certain properties with other members of the glycopeptide class of antibiotics, which includes vancomycin, the current standard of care for serious Gram-positive infections in the United States and Europe. It … See more Oritavancin is active against gram-positive aerobic bacteria such as enterococci, staphylococci, streptococci, and anaerobic bacteria such as Clostridium difficile , Clostridium perfringens , Peptostreptococcus spp. , and Propionibacterium acnes. See more • "Oritavancin". Drug Information Portal. U.S. National Library of Medicine. See more In 2003, results were presented from two pivotal phase-III clinical trials testing the efficacy of daily intravenous oritavancin for the treatment of acute bacterial skin and skin-structure infections See more Originally discovered and developed by Eli Lilly, oritavancin was acquired by InterMune in 2001 and then by Targanta Therapeutics in … See more WebORBACTIV is intended for intravenous infusion, only after reconstitution and dilution. Three ORBACTIV 400 mg vials need to be reconstituted and diluted to prepare a single 1200 mg …
WebOct 5, 2016 · A Double-Blind, Randomized Study to Evaluate the Safety of Either a Single 1200-mg Intravenous (IV) Dose of Orbactiv™ (Oritavancin) and Placebo or Two IV Doses of Orbactiv™ in Subjects Being Treated for Acute Bacterial Skin and Skin Structure Infection (ABSSSI) Actual Study Start Date : January 2024: Actual Primary Completion Date : June …
WebSep 1, 2014 · Orbactiv is intended for intravenous infusion, only after reconstitution and dilution. Three Orbactiv 400 mg vials need to be reconstituted and diluted to prepare a … phillip o\u0027reillyWebORBACTIV® (oritavancin) for injection is indicated for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused or suspected to be caused by susceptible isolates of the following gram-positive microorganisms: Staphylococcus aureu s (including methicillin-susceptible [MSSA] and -resistant [MRSA] … tryp wuppertalWebFeb 25, 2024 · Orbactiv Dosage Generic name: ORITAVANCIN 400mg Dosage form: injection, powder, lyophilized, for solution Drug class: Glycopeptide antibiotics Medically … phillip pacheco troy police deptWebORBACTIV® (oritavancin) for injection is indicated for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused or suspected to be … phillippa bradleyWebThe efficacy and safety of KIMYRSA were established in the SOLO clinical trials with another oritavancin product, ORBACTIV ®. The SOLO trials were randomized, double-blind, multicenter studies that evaluated a single 1,200 mg IV dose of oritavancin against twice-daily vancomycin for the treatment of ABSSSI in 1,987 adult patients and assessed ... phillippa carisbrookeWebJun 19, 2024 · Hydration (oral intake if possible) Cold compresses Elevation and rest of the affected limb: Recommended to reduce local swelling, inflammation, and pain Saline wet dressings: Should be applied to... tryp windham nyWebFeb 16, 2024 · Headache. Irritation where the shot is given. Diarrhea, upset stomach, or throwing up. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. phillip ousley