Forkhead associated domain
WebSep 18, 2003 · Forkhead-associated (FHA) domains are phosphoprotein-binding modules found in diverse signaling proteins that bind partners phosphorylated on threonine or serine. Kinase-associated protein phosphatase from Arabidopsis employs its FHA domain for negative regulation of receptor-like kinase signaling pathways, which are important in … WebMar 1, 2024 · Here, we uncover a role for the Fkh1 (Forkhead homolog) protein, and, in particular, its forkhead associated (FHA) domain in promoting ORC-origin binding and origin activity at a subset of origins in Saccharomyces cerevisiae. The majority of the FHA-dependent origins within the experimental subset examined contain a distinct Fkh1 …
Forkhead associated domain
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WebFeb 25, 2024 · found that forkhead-associated domain 2 (FHA2) negatively regulates miRNA biogenesis. It interacts with DCL1 to repress pri-miRNA processing. Remarkably, … WebApr 10, 2024 · The FOX family contains two domains: a forkhead winged helix–turn–helix DNA binding domain, which directly binds to the promoter region of DNA to regulate gene transcription, and a forkhead-associated (FHA) domain, which interacts with proteins that recognize phosphopeptides .
WebForkhead-associated (FHA) domains are small phosphopeptide recognition modules found in eubacterial and eukaryotic, but not archeal, genomes. Although they were … WebForkhead-associated (FHA) domains are a pThr-binding module found in several prokaryotic and eukaryotic proteins, including kinases, phosphatases, transcription factors, kinesin …
WebForkhead associated domain There are 73373 FHA domains in 68942 proteins in SMART's nrdb database. Click on the following links for more information. Evolution (species in which this domain is found) Cellular role (predicted cellular role) Literature (relevant references for this domain) http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00240
WebHere, we describe the ability of a virally encoded form of the Pellino protein to inhibit Toll- and TLR-mediated activation of downstream Rel family transcription factors. In addition to inhibiting drosomycin promoter activation by Sptzle in Drosophila melanogaster cells, viral Pellino attenuates the activation of NF-κB by TLR signalling ...
WebAug 21, 2015 · In its C terminus, a tandem BRCA1 C-terminal domain binds phosphorylated histone H2AX, and in its N terminus, a forkhead-associated (FHA) domain mediates a phosphorylation-enhanced homodimerization. The FHA domain of the Drosophila homolog of MDC1, MU2, also forms a homodimer but utilizes a different dimer interface. The … epit research labs private limitedWebFeb 20, 2002 · The forkhead-associated (FHA) domain is a small protein module recently shown to recognize phosphothreonine epitopes on proteins. It is present in a diverse … epi training onlineWebIt was first reported in 2008 by a Chinese study that in diabetic patients, serum RBP4 levels in the third tertile were associated with an increased risk of NAFLD compared with those with RBP4 levels in the first tertile (OR: 9.897, 95% CI: 2.281-42.936; P < 0.001). [] Another study conducted in Korea also revealed that in nondiabetic adults, the serum RBP4 level … epitrimerus integrae xue song \\u0026 hong 2007 pdf