WebFeb 26, 2024 · R-loops are three-stranded DNA/RNA hybrids that form by the annealing of the mRNA transcript to its coding template while displacing the non-coding strand. While R-loop formation regulates physiological genomic and mitochondrial transcription and DNA damage response, imbalanced R-loop formation can be a threat to the genomic integrity … WebNov 2, 2010 · Chromodomain-helicase-DNA-binding protein 4 EC number EC:3.6.4.12 ( UniProtKB ENZYME Rhea) 1 publication Short names CHD-4 Alternative names ATP …
CHD4 - Chromodomain-helicase-DNA-binding protein 4
WebJun 4, 2012 · Chromodomain helicase DNA-binding protein 4 (CHD4) is an ATP-dependent chromatin remodeler involved in epigenetic regulation of gene transcription, DNA repair, and cell cycle progression. Also known as Mi2β, CHD4 is an integral subunit of a well-characterized histone deacetylase complex. Here we report five individuals with de … WebApr 26, 2024 · Chromodomain-helicase-DNA-binding protein 4 (CHD4) is an epigenetic regulator identified as an oncogenic element that may provide a novel therapeutic target … inat box pro indir
CHROMODOMAIN HELICASE DNA-BINDING PROTEIN 7; CHD7
WebApr 14, 2024 · Eukaryotic DNA replication is catalyzed by a MDa-sized dynamic protein complex known as the replisome. The replisome is powered by the replicative helicase … WebFeb 24, 2012 · Here, we report that chromodomain helicase DNA-binding protein 4 (CHD4) is a novel BRIT1 binding partner that regulates the HR repair process. The BRCA1 C-terminal domains of BRIT1 are required for its interaction with CHD4. Depletion of … WebFeb 24, 2012 · Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to … in accordance with the instructions